BackgroundObtaining informed consent for participation in genomic research in low-income settings presents specific ethical issues requiring attention. These include the challenges that arise when providing information about unfamiliar and technical research methods, the implications of complicated infrastructure and data sharing requirements, and the potential consequences of future research with samples and data. This study investigated researchers’ and participants’ parents’ experiences of a consent process and understandings of a genome-wide association study of malaria involving children aged five and under in Mali. (...) It aimed to inform best practices in recruiting participants into genomic research.MethodsA qualitative rapid ethical assessment was undertaken. Fifty-five semi-structured interviews were conducted with the parents of research participants. An additional nine semi-structured interviews were conducted with senior research scientists, research assistants and with a member of an ethics committee. A focus group with five parents of research participants and direct observations of four consent processes were also conducted. French and translated English transcripts were descriptively and thematically coded using OpenCode software.ResultsParticipants’ parents in the MalariaGEN study had differing understandings of the causes of malaria, the rationale for collecting blood samples, the purposes of the study and the kinds of information the study would generate. Genomic aspects of the research, including the gene/environment interaction underlying susceptibility or resistance to severe malaria, proved particularly challenging to explain and understand.ConclusionsThis study identifies a number of areas to be addressed in the design of consent processes for genomic research, some of which require careful ethical analysis. These include determining how much information should be provided about differing aspects of the research and how best to promote understandings of genomic research. We conclude that it is important to build capacity in the design and conduct of effective and appropriate consent processes for genomic research in low and middle-income settings. Additionally, consideration should be given to the role of review committees and community consultation activities in protecting the interests of participants in genomic research. (shrink)

A Treasury of the Buddha's Words: Discourses from the Middle Collection. Translated by Nanamoli Thera, edited and arranged by Phra Khantipalo. 3 vols, Mahamakut, Bangkok, but available only from Wat Buddha-Dhamma, Ten Mile Hollow, Wisemans Ferry, NSW 2255, Australia.

Il Cuore della Meditazione Buddhista. Nyanaponika Thera, translated into Italian by Nazzareno Ilari. Ubaldini Editore, Rome 1978, 209 pp. Lire 6000.

A Thinker's Note Book.. Published, edited and introduced by Ven. Nyanaponika, Forext Hermitage Kandy. 254pp.

This article first briefly examines the textual structure of the Vangisathera Samyutta of the Pali Samyutta-nikaya in conjunction with two other versions preserved in Chinese translation in Taisho vol. 2, nos. 99 and 100. Then it compares the main teachings contained in the three versions. These three versions of this collection on the subject of the venerable Vangisa represent three different early Buddhist schools within the Sthavira branch. This comparative study of these three different versions focuses on three major topics: (...) Arhants at the pravarana ceremony; sensual desire and the way to extinguish it; and the Buddha’s teachings to Vangisa. It reveals similarities and significant differences in structure and doctrinal content, thus advancing the historical/critical study of early Buddhist doctrine in this area. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Abhidhamma Studies: Buddhist Explorations of Consciousness and TimeDouglas W. ShraderAbhidhamma Studies: Buddhist Explorations of Consciousness and Time. By Venerable Nyanaponika Thera. Fourth edition. Edited with an introduction by Bhikkhu Bodhi. Boston: Wisdom Publications, 1998. Pp. 160. Paper $16.95.The delightful, thought-provoking Abhidhamma Studies: Buddhist Explorations of Consciousness and Timeby the Venerable Nyanaponika Thera is the fourth incarnation of a text originally composed shortly after World (...) War II, published in 1949 (Frewin and Co., Ltd.). The Buddhist Publication Society issued a second, revised and enlarged edition in 1965 as well as a third edition, with relatively minor corrections, in 1976. The present edition, edited by Bhikkhu Bodhi, incorporates a variety of welcome changes, reflecting considerable effort and devotion to the task. In addition to authoring a superb introductory essay, Bodhi has "reformulated a few awkward sentences..., reorganized the notes, provided additional references, and supplied a bibliography" (p. viii). Perhaps the most intriguing and potentially significant change is evident in the title itself. Originally subtitled Researches in Buddhist Psychology, an apt but relatively uninformative description of its contents, the title now announces, even to the uninitiated, the book's unique, captivating subject matter: Buddhist Explorations of Consciousness and Time.This book is essential reading for any serious student of Buddhism. Additionally, it will appeal to those interested in a wide variety of both phenomenological and ontological issues: the manifold of experience, the nature of consciousness, the analysis of time, concepts of anattā(ego selflessness) and paticca-samuppāda(dependent origination), and so forth. An intermediate to advanced level of familiarity and understanding of basic Buddhist doctrines is recommended. It will prove particularly useful to scholars and students who have been intimidated by the vast, often cryptic, Abhidhamma literature.Apparently, the Buddha and his teachings were as enticing and yet profoundly puzzling and enigmatic to his contemporaries and followers as they remain to millions today. They challenge everything we commonly take to be real. That which appears substantial, we are told, is not. Contrary to our own (unexamined) inner/ subjective experience, as well as the teachings of most major world religions, we neither arenor havea self, for there is no self either to be or to have. The attempt to reconcile the teachings of the Buddha with existing beliefs and assumptions concerning the nature of reality led to a proliferation of competing philosophical schools. Each school developed its own distinctive Abhidhamma literature, ostensibly representing a deeper understanding of the teachings of the Buddha. In practice, the literature served to distinguish one school from another, guarding against and/or [End Page 637]correcting the "erroneous" teachings of the other schools. Over a period of approximately three centuries, the Abhidhamma Pitaka grew rapidly…in terms of the sheer volume of literature as well as complexity of doctrine. Paralleling that increase, it came to play a position of ever greater prominence, rivaling even the canonical collections of the Buddha's word (the Sutta and Vinaya Pitakas). Together the three became known as the Tipitaka: "Three Baskets of the Doctrine."Unfortunately for scholars, the only Abhidhammas to survive the widespread persecution of Buddhism in India during the twelfth century A.D.were those that had been transported to, and transplanted in, other lands. Specifically, the Theravāda Abhidhamma (seven books in Pāli) found an enduring home in Sri Lanka. The Sarvāstivāda Abhidhamma (also seven books) along with the Śāriputra-abhidharmaśāstra(probably the Dharmaguptaka School) were carried to China, where they were translated from Sanskrit into Chinese. Of these, it is the Theravaāda collection— particularly its first book (the Dharmasanganī) as well as the seventh book (the Patthana)—that forms the subject matter of Ven. Nyanaponika's study. The other two schools have long since vanished, except, as Bhikkhu Bodhi points out, that "a late exposition of the Sarvāstivāda Abhidhamma system, Vasubandhu's Abhidharmakośa, continues to be studied among Tibetan Buddhists and in the Far East" (p. x).Abhidhamma Studiesis divided into five chapters and two appendixes. Chapter 1, which was added in the second edition, provides a brief historical overview of "The Abhidhamma Philosophy." Those who approach the Abhidhamma... (shrink)

Journal of the Pali Text Society. IX. Ed. by K. R. Norman. PTS and distributed by Routledge, Kegan Paul Ltd, London 1981. viii + 207 pp. £10.

Catalog of the collection of the Madamkhand Museum of Art, named after the wife of Batzhargalyn Batbai︠a︡r, businessman and member of the Mongolian Khural.

This essay brings psychoanalytic theory on trauma together with film and television criticism on rape narrative in an analysis of Michael Coel’s 2020 series I May Destroy You. Beyond the limited carceral framework of the police procedural, which dislocates the act of violence from the survivor’s history and context, Coel’s polyvalent, looping narrative metabolizes rape television’s forms and genres in order to stage and restage both trauma and genre again and anew. Contesting common conceptions of vulnerability and susceptibility that prefigure (...) a violent breach of autonomy, Coel’s series and her interviews about it invite an ethics of looking that embraces a curiosity in the unknowable and untreatable kernel of subjective experience and defies and resists a policing of the survivor’s thoughts and emotions. By emphasizing and exploring what psychoanalysis calls the “afterwardness” of trauma, Coel foregrounds her main character’s subjectivity prior to her victimization, widens the sphere of consequence beyond the victim and criminal justice system to the survivor’s larger community, and entreats that community to preserve a space for her to look and look again at everything, without judgment. (shrink)

Modern scholars have been concerned with the hostility shown to Alexander by the Hellenistic schools of philosophy. Two literary portraits have been distinguished, the Peripatetic and the Stoic, the former deriving from Theophrastus' book on Callisthenes, or starting with this work the Peripatetics worked out a theory of and applied it to Alexander, in order to belittle his achievements. It was a case of giving sophisticated expression to the kind of crude resentment expressed by Demades.

Introduction: Conversion and the practice of transformation -- The philosophical structure of Jonathan Edwards's religious affections -- Habit, habit change, and conversion in C.S. Peirce -- Reconstructing faith : religious overcoming in Dewey's pragmatism -- Transforming obligation in William James -- Dwelling in absence: the reflective origin of conversion -- Creative transformation : the work of conversion -- The evasion of conversion in recent American philosophy.

Les Prolegomenes a la Philosophie de Platon sont un manuel d'ecole neoplatonicien. Il s'inspire d'un modele dont Proclus a du etre l'auteur, mais l'origine de ce texte est presque surement alexandrine et doit dater de la premiere moitie du Vle siecle. Cette oeuvre est essentielle pour comprendre comment etait diffuse l'enseignement platonicien, et pour mieux saisir le mouvement des idees de l'Antiquite finissante. Dans une importante introduction, L. O. Westerink a retrace l'histoire de l'ecole d'Alexandrie et celle du genre litteraire (...) de ces introductions a Platon et a Aristote. (shrink)

In the twenty-first century, the debate about life on other worlds is quickly changing from the realm of speculation to the domain of hard science. Within a few years, as a consequence of the rapid discovery by astronomers of planets around other stars, astronomers very likely will have discovered clear evidence of life beyond the Earth. Such a discovery of extraterrestrial life will change everything. Knowing the answer as to whether humanity has company in the universe will trigger one of (...) the greatest intellectual revolutions in history, not the least of which will be a challenge for at least some terrestrial religions. Which religions will handle the discovery of extraterrestrial life with ease and which will struggle to assimilate this new knowledge about our place in the universe? Some religions as currently practiced appear to only be viable on Earth. Other religions could be practiced on distant worlds but nevertheless identify both Earth as a place and humankind as a species of singular spiritual religious importance, while some religions could be practiced equally well anywhere in the universe by any sentient beings. Weintraub guides readers on an invigorating tour of the world's most widely practiced religions. It reveals what, if anything, each religion has to say about the possibility that extraterrestrial life exists and how, or if, a particular religion would work on other planets in distant parts of the universe. (shrink)

Purpose. To examine the existential anthropology of G. Marcel and E. Minkowski, in order to demonstrate the necessity of distinguishing the universal-spiritual, as human in human being, apart from the individual-existential in him, and to reveal the hierarchical correlation of biosocial, existential and spiritual spheres in personality. Theoretical basis. Within existential philosophy the author differentiates two separate traditions and proceeds from the insufficiency of the distinction of existential sphere, proposed by phenomenological tradition, showing the necessity of its correlation with the (...) spiritual sphere as a sphere of humanity, proposed by non-phenomenological tradition of G. Marcel and E. Minkowski. Originality. The author presents the anthropological conception of G. Marcel and E. Minkowski, in which human personality is understood as unity of individual-existential and universal-spiritual, which requires a special trans-empirical field of culture, which contains senses, images and symbols of humanity. Also, the author presents the recent developments of existential thinkers in distinguishing existential and spiritual dimensions, both not reducible to the physical and social dimensions. Conclusions. In both existential traditions, the specifically human was founded as a trans-biological and trans-social phenomenon, which appears as indefinable and non-predetermined. But in first tradition, humanity is understood as an existence, as a unique individuality, "project", variant of humanity, equivalent to other variants, and universal is understood as a community of human condition in the world. While in the second tradition, the universal is understood as spiritual. Thus, horizontal level of our private existence, as the process of movement from birth to death, is supplemented by vertical of human, universal ideals and images. Humanity appears as a task, on the way to which human being transcends beyond the limits of his individual "self" to the "super-individual", through inclusion into spiritual community, into universal culture. (shrink)

The phenomenon of altruism extends from the biological realm to the human sociocultural realm. This article sketches a coherent outline of multiple types of altruism of progressively increasing scope that span these two realms and are grounded in an ever-expanding sense of “self.” Discussion of this framework notes difficulties associated with altruism at different levels. It links scientific ideas about the evolution of cooperation and about hierarchical order to perennial philosophical and religious concerns. It offers a conceptual background for inquiry (...) into societal challenges that call for altruistic behavior, especially the challenge of environmental and social sustainability. (shrink)

The locus classicus for Plutarch's own views on his methods is in the Alexander He has begun by asking for the indulgence of his readers if they do not find all the exploits of Alexander and Caesar recounted by the biographer or if they discover him not reporting some famous incident in detail (); and he goes on to compare his own search for evidence which will indicate the kind of soul, with the activity of the painter, who, in order (...) to create a likeness, concentrates on the eyes and pays little attention to the other parts. Commentators and critics have been right to take this as a key text for the purpose of understanding Plutarch's attitude towards his biographical work; nevertheless there are other passages in the Lives where we can at least glimpse his attitude to his subject, and we can only see the Alexander-remarks in correct perspective if we take these other passages into account. I propose therefore, starting with the Alexander, to see how far these critical remarks apply to Plutarch's theory and practice elsewhere in the Lives. (shrink)

According to the Ars Amatoria the notorious rape took place on the occasion of a primitive dramatic entertainment staged in a theatre, in which the seats and furnishings were also primitive. There is no time for a description of the arts of the performers—a tibicen and a ludius—before the Romans, impatient for action, receive their signal from Romulus. Nor is there any mention of a god in whose honour the entertainment had been provided.